Long term effects of meth on the brain
You cannot predict how long or severe effects of meth will last. Psychologically, you may experience cravings for years. Physiologically, prolonged meth use can cause permanent changes to the brain. So what are some of the specific effects of meth on the brain? More here, with a section for your questions at the end.
Specific long term effects on the brain
On the nervous system

- chronic fatigue
- impaired verbal learning
- insomnia
- reduced motor skills
On the neurotransmitters
- blocks the re uptake of the brain chemical dopamine
- destroys dopamine receptors
- increased tolerance for amphetamines
- increases the release of dopamine
- makes it impossible to feel pleasure
On the personality
- aggressive behavior
- irritability
- paranoia
- violent behavior
On behavior
- anti-social or aggressive
- compulsive repetition of meaningless acts
- compulsive tooth grinding
- disorganized lifestyle
- neglect of regular brushing and flossing
- strong desire for sugary foods and drinks
Psychological effects
- anhedonia absence of pleasure
- antisocial personality disorder
- anxiety
- major depressive episodes
- manic episodes
- mood disturbances
- obsessive compulsive disorder
- panic disorder
- paranoia
- phobias
- psychosis
- schizophrenia
What are typical doses?
Medicinal typical doses (methampehtamine is not recommended more than 6 weeks)
- per day …… 10 to 40 mg
- per week ……… 70 to 280 mg
Abuse typical doses
- per day ………… 100 to 1000 mg
Chronic binge use
- per day ………… 5000 mg
How long is “long term”?
Daily use of meth for few weeks or more.
Chronic = habitual meth abuse that substantially injures:
- economic
- health
- social
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