Long term effects of meth on the brain (INFOGRAPHIC)

Meth causes specific effects on the brain. We’ve compiled them graphically here. If you like it, support us by LIKE > SHARE > PRINT for use in the classroom or medical office.

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Long term effects of meth on the brain

You cannot predict how long or severe effects of meth will last. Psychologically, you may experience cravings for years. Physiologically, prolonged meth use can cause permanent changes to the brain. So what are some of the specific effects of meth on the brain? More here, with a section for your questions at the end.

Specific long term effects on the brain

On the nervous system

Long term effects of meth on the brain (INFOGRAPHIC)

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  • chronic fatigue
  • impaired verbal learning
  • insomnia
  • reduced motor skills

On the neurotransmitters

  • blocks the re uptake of the brain chemical dopamine
  • destroys dopamine receptors
  • increased tolerance for amphetamines
  • increases the release of dopamine
  • makes it impossible to feel pleasure

On the personality

  • aggressive behavior
  • irritability
  • paranoia
  • violent behavior

On behavior

  • anti-social or aggressive
  • compulsive repetition of meaningless acts
  • compulsive tooth grinding
  • disorganized lifestyle
  • neglect of regular brushing and flossing
  • strong desire for sugary foods and drinks

Psychological effects

  • anhedonia absence of pleasure
  • antisocial personality disorder
  • anxiety
  • major depressive episodes
  • manic episodes
  • mood disturbances
  • obsessive compulsive disorder
  • panic disorder
  • paranoia
  • phobias
  • psychosis
  • schizophrenia


What are typical doses?

Medicinal typical doses (methampehtamine is not recommended more than 6 weeks)

  • per day …… 10 to 40 mg
  • per week ……… 70 to 280 mg

Abuse typical doses

  • per day ………… 100 to 1000 mg

Chronic binge use

  • per day ………… 5000 mg

How long is “long term”?

Daily use of meth for few weeks or more.

Chronic = habitual meth abuse that substantially injures:

  • economic
  • health
  • social
About the author
Lee Weber is a published author, medical writer, and woman in long-term recovery from addiction. Her latest book, The Definitive Guide to Addiction Interventions is set to reach university bookstores in early 2019.


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  1. Hello, I am reading the messages left here. Do people buy this crap??? oh man!! Actually, I am doing research for a term paper. I would like to use these the information shown here on your site as drug propaganda. Can you tell me where one found the statistics listed here?
    I appreciate the time and cooperation.

    1. Hi Hillary. We are all for good research and information gathering. Here are a few of the links we used to extract information from, maybe you can use them to extract some well-informed conclusions for your school work.

      1) TYPICAL DOSES: https://one.nhtsa.gov/people/injury/research/job185drugs/methamphetamine.htm Please note the “Medical and Recreational Uses” section: “Typical doses are 10 mg/day or up to 40 mg daily, and a course of greater than six weeks is not recommended.” AND “Potency, Purity and Dose” section: “Common abused doses are 100-1000 mg/day, and up to 5000 mg/day in chronic binge use.”

      – NIDA: Substance Induced Disorders (scroll to the cocaine and amphetamine section) https://www.ncbi.nlm.nih.gov/books/NBK64178/
      – NIDA: Health Consequences of Drug Misuse (Neurological Effects) https://www.drugabuse.gov/publications/health-consequences-drug-misuse/neurological-effects
      – NIDA: Mind Over Matter: Methamphetamine (Meth) https://teens.drugabuse.gov/teachers/mind-over-matter/methamphetamine
      – U.S. Department of Justice: Drug Abuse and Mental Illness Fast Facts https://www.justice.gov/archive/ndic/pubs7/7343/

      Good luck with your term paper!

  2. Thank you for these articals only wish i knew back then..but after reading the facts..i now can say never again..maybe insted of pics to scare people use facts..Again thank you..i suffered for 14 years..and had a slip..but reading facts brought me to tears

  3. I usees meth for 3 plus years in the 80’s. How long do the paranioa, and violent behavior effects last after one stop using? I drink in excess at times, and am wondering if my past meth use is still a facter, or is it the alcohol only.

  4. I am in a lot of trouble legally. I think my meth habit maybe the reason I thought it was ok? when I think about it I do not believe it was me. Have I gone insane?? Where can I get answers

    1. Hi Hank. Your meth habit may be the reason for your problems. Think about what happen to you and what were the reason for your wrongdoings.

  5. I have smoke reguerly for 6months and i was chain smoker also but now it has been 5yrs since i left smoking.. Do you think ita still in my lungs ? Coz i am having health issues from last 5years specially errectical dysfunction and pain in my chest and i sneeze alot

I am ready to call
i Who Answers?