The Oxycodone Withdrawal Timeline Chart

A detailed VISUAL GUIDE to oxycodone withdrawal symtoms.

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What Is Oxycodone Withdrawal?

Oxycodone is used for treating moderate to severe pain. It is a synthetic opioid medication with habit forming risk. In fact, using this medication daily for a period of a few weeks or more can lead physical as well as psychological dependence. If you’re dependent on oxycodone and you cut down the daily dose or completely stop using oxycodone at once, you can expect to experience a set of predictable oxycodone withdrawal symptoms.

  • How long does withdrawal from oxycodone last?
  • What are oxycodone withdrawal symptoms?
  • When do symptoms occur in the days, weeks, and months after you quit?

We answer these questions here. Explore our detailed drug withdrawal infographic to find out! If you find it educational, feel free to use it, or share it with those in need! The embed code is under the image. And, if you have any questions, please leave them below. We try to respond to all real-life questions personally.

The Oxycodone Withdrawal Timeline Chart

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Oxycodone Withdrawal Timeline

The cluster of predictable oxycodone withdrawal symptoms usually begin 4-6 hours after the last dose intake. This is because withdrawal is triggered as soon as oxycodone starts to leave the system. Withdrawal symptoms typically peak 72 hours after the cessation, while the time it takes to completely resolve all symptoms varies from person to person. Generally, withdrawal from oxycodone can last for few days to several weeks. Withdrawal lasts longer when you:

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  • Use oxycodone at high doses
  • Use oxycodone for a period of 3 months or more
  • Take oxycodone multiple times per day

What are the main symptoms of oxycodone withdrawal? Check out the list below to find all oxycodone symptoms of withdrawal with a general time frame for their appearance:

0-48 Hours After Last Oxycodone Dose:

  • Abdominal cramps
  • Anxiety
  • Cravings
  • Depression
  • Diarrhea
  • Irritability
  • Loss of appetite
  • Muscle aches
  • Nausea
  • Runny nose
  • Sleep disorders
  • Sweating

3-5 days after Oxycodone Cessation:

  • Anxiety
  • Body pain
  • Cravings
  • Depression
  • Sleep disorders
  • Tremors

6-7 days of Oxycodone Withdawal:

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  • Anxiety
  • Depression
  • Diarrhea
  • Irritability
  • Mood swings
  • Nausea

Week 2 of Oxycodone Withdawal:

  • Cravings stabilization
  • Feeling better

How Long To Withdrawal From Oxicodone?

How long does withdrawal from oxycodone last? Oxycodone withdrawal can last anywhere between a few days to weeks. It depends from person’s general health, frequency, and dosage.

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NOTE: Long-term oxycodone users may experience post acute withdrawal symptoms a.k.a. PAWS that can last for a longer period of time.

The most common oxycodone PAWS include:

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  • Anxiety
  • Depression
  • Lack of motivation
  • Mood swings

How can you treat oxycodone withdrawal? The safest way to manage withdrawal from oxycodone is under medical supervision. With the help of experienced and trained medical staff, you’ll get all support you need!

Oxycodone Withdrawal Timeline Questions

Do you struggle with oxycodone withdrawal? Ready for help? Call 1-877-721-4914 to get in touch with a trusted addiction recovery consultant! This helpline is free, and available any time of the day or night.

Still have questions? If you still have questions about this oxycodone infographic, please post them in the comments section at the end. We are happy to try to answer your real-life questions personally and promptly.

Reference Sources: Food and Drugs Administration: Drugs Class Information
Medline Plus: Oxycodone
PubChem: Oxycodone Compete Summary
NIDA: The Neurobiology of Opioid Dependence: Implications for Treatment
SAMHSA: Clinical Guidelines for the Use of Buprenorphine in the Treatment of Opioid Addiction, 4 Treatment ProtocolsUtah Department of Health: Utah Clinical Guidelines on Prescribing Opioids for Treatment of Pain, Strategies for Tapering and Weaning
About the author
Lee Weber is a published author, medical writer, and woman in long-term recovery from addiction. Her latest book, The Definitive Guide to Addiction Interventions is set to reach university bookstores in early 2019.


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