The Buprenorphine Withdrawal Timeline Chart

A graphic display of Buprenorphine Withdrawal Symptoms. Learn what to expect here:

minute read

What is Buprenorphine Withdrawal?

As a partial mu-receptor opiate agonist,daily buprenorphine use can lead to physical dependence. Although dependence is the natural and expected adaptation of your body to the medicine, getting of buprenorphine can be very uncomfortable. Ending the conditions starts with withdrawal, which is best managed from a medical detox clinic.

But, what can you expect during buprenorphine withdrawal?
How long does withdrawal from buprenorphine last?
And what symptoms occur when?

The Buprenorphine Withdrawal Timeline Chart

Embed this infographic to your website

We invite you to explore our easy-to-follow visual presentation for more answers. If you have any questions and comments, feel free to post them in the comments section below. We’re eager to see what you think. Finally, we do our best to answer personally and promptly to all legitimate inquiries. So reach out via the comments form! We’ll get back to you ASAP.


Need Help NOW?
Call 1-877-736-9802.
Addiction Recovery Specialists 24/7.


Buprenorphine Withdrawal Timeline

The first withdrawal symptoms occur when the last dose of buprenorphine wears off, and they usually peak at around 72 hours after the last intake. Withdrawal from buprenorphine is reported to be milder in its severity in comparison to the withdrawal from heroin or other stronger opiates.  However, some symptoms can persist for days, weeks, or months after acute withdrawal end.

What are the symptoms of buprenorphine withdrawal? It can basically feel like you caught a bad flu. We explain below with a detailed easy-to-understand schedule of symptom occurrence:

24-72 hours after the last dose of buprenorphine:

  • Diarrhea
  • Dilated pupils
  • Nausea
  • Restlessness
  • Sweating
  • Watery eyes

3-7 days after the last dose of buprenorphine:

  • Abdominal cramps
  • Anxiety
  • Body aches
  • Depression
  • Mood swings
  • Sleep disorders

Week 2 Buprenorphine Withdrawal:

  • Abdominal cramps
  • Body pain
  • Cravings
  • Depression
  • Irritability
  • Lack of motivation

Week 3 Buprenorphine Withdrawal:

  • Body pain stabilization
  • Cravings
  • Depression
  • Mood swings

Week 4 Buprenorphine Withdrawal:

  • Confusion
  • Decreased cravings
  • Feeling better
  • Irritability

How Long Does Withdrawal Last?

The length of buprenorphine withdrawal varies from person to person, and it depends from the frequency and dosage of buprenorphine use. Many heavy buprenorphine abusers may experience protracted acute withdrawal syndrome (PAWS) which can last from a few weeks to several months.

Buprenorphine PAWS may include:

  • Anxiety
  • Brain fog
  • Depression
  • Memory loss
  • Sleep disorders
  • Stress

How to treat buprenorphine withdrawal? The safest and the best way to manage withdrawal is to enroll into a rehab program where you can receive help and support for both, the physical and physiological aspects of detox and the challenges they pose.

You don’t have to suffer in silence, there’s a better way out!

Buprenorpine Withdrawal Questions

If you’re struggling with buprenorphine withdrawal, and you like to make sobriety your priority, CALL 1-877-736-9802 TODAY to speak with addiction professionals who will help you turn your life around and find the best treatment option for you. Our team is available 24/7/365 to help you find and locate a detox center or a treatment facility.

It’s simple…just pick up the phone!

If you still have questions about buprenorphine withdawal timeline – send them to us. Please feel free to use the comments below to direct all questions to our caring and compassionate staff. We try to respond to all legitimate inquiries ASAP. In case we don’t know the answer to your question, we will gladly refer you to professionals who can help.

Reference Sources: NCBI: Buprenorphine withdrawal
National Drug Intelligence Center: Buprenorphine: Potential for Abuse
NY State Department of Health: Buprenorphine: A New Drug for Treating Heroin Addiction
SAMSHA: The Facts About Buprenorphine
About the author
Lee Weber is a published author, medical writer, and woman in long-term recovery from addiction. Her latest book, The Definitive Guide to Addiction Interventions is set to reach university bookstores in early 2019.


Leave a Reply

Your email address will not be published. Required fields are marked *

I have read and agree to the conditions outlined in the Terms of Use and Privacy Policy.

  1. I have only been taking 10mg total per day for about a month. I put myself in detox on 12/27/18 to get off Percocet. It was suggested that I only reduce 2mg every 2 weeks but I just want to be off sooner. I have noticed myself changing my dosing schedule around. Like taking 8 mg at once and taking more one day less another. Taking what I think I need not how it’s prescribed. (4mg/am, 4mg/noon, 2mg/pm) I have desire to refill my prescription on the 5 !! I have approximately 15/8mg tablets left and just want to ween off with these. Is that possible and how sick will I get ?

    1. Hi Sharon. Not taking your pills as prescribed can be dangerous and can lead to dependence. Also, withdrawal is different for everyone. It will depend on how long have you been using,how much, and your overall health. It doesn’t necessarily mean that you will get sick. In situations like these, it is advisable that you consult with your prescribing doctor so they can plan a tapering schedule according to you needs. They can develop the est plan. If that doesn’t help, you always have the option of a medical detox in a clinic, where you can safely taper off and will be closely monitored by professionals. Call us if you need more info about detox programs.

  2. I am on day 13 of going Cold Turkey. My doctor is an MD who specializes in this. He is also a PharmD as well as a psychiatrist. He has been amazingly helpful and I attribute following his directions and having the willpower to say, I AM DONE! Has it been uncomfortable and was I looking forward to it? I knew what I was in for and wasn’t disappointed. However, You must do the thing that you cannot do! He saved my life. I went for back pain, am highly educated and did not realize how addicted I would become to opiates. My wonderful doctor never judged me and every drug screen that was required were negative. He said that he did not like to lecture because I was hard enough on myself. I am thinking in 2 more weeks, it will be much better. I just thank God I found him. And if you don’t pray, you need to start. It has helped me tremendously and I have no shame to say I am a Christian. Best of luck to all of you. You CAN do it!

  3. How the fuck do you treat somthing hard to get off of with something even harder to get off of? This is fucked.I guess you just stay on sub forever?? b.s.!

I am ready to call
i Who Answers?