Methadone side effects

Methadone treatment for opiate addiction can be effective. But some doctors can be critical of the practice, usually an opinion based in ignorance of methadone and how it works. Dr. Jana Burson reviews the full spectrum of methadone side effects here, clearly outlining methadone side effects on the body so that you can be better informed.

minute read
Reviewed by: Dr. Dili Gonzalez, M.D. Dr. Juan Goecke, M.D.

ARTICLE OVERVIEW: Methadone is a synthetic narcotic. It is used legally to treat addiction to narcotics and to relieve severe pain. Main adverse side effects include sedation, respiratory problems, and sexual dysfunction. More on the PROs and CONs of this very controversial medication here.


What Is Methadone?

Methadone is a synthetic, long-acting opioid with pharmacologic actions qualitatively similar to morphine. It is a synthetic opiate primarily used in the detoxification and maintenance of persons who are dependent on opiates and the treatment of persons with chronic, severe pain.

Methadone has been used for decades to treat people who are addicted to heroin and narcotic pain medicines. When taken as prescribed, it is safe and effective. It allows people to recover from their addiction and to reclaim active and meaningful lives. For optimal results, persons should also participate in a comprehensive medication-assisted treatment program that includes counseling and social support. [1]

How It Works

Methadone is active by oral and parenteral routes of administration. It works by changing how the brain and nervous system respond to pain. In particular, methadone, like other opioids, acts by engagement in cell surface opiate receptors (predominant µ type receptors). It is a controlled substance and classified as a Schedule II drug, indicating that it has medical usefulness, but also a high potential for physical and psychological dependency and abuse. In fact, use of methadone as a part of a medication assisted treatment program requires special certification.

In sum, methadone can lessen pain, delay symptoms of opiate withdrawal, and block the euphoric effects of opiate drugs such as heroin, morphine, and codeine, as well as semi-synthetic opioids like oxycodone and hydrocodone.


Methadone onset of action takes from 30-60 minutes with peak effects at 1-2 hours. Its effects Methadone is offered in pill, liquid, and wafer forms and is taken once a day. Pain relief from a dose of methadone lasts about four to eight hours. When used to treat narcotic addiction, methadone suppresses withdrawal symptoms for 24 to 36 hours and while the dose is highly individualized, maintenance doses are generally in the range of 20 to 120 mg daily. Review more information on the pharmacology of methadone in this Duke University Narcotics Analgesics video, Specific Analgesic Agents: Methadone…about minute 31:30. [2]

Therapeutic Effect

Methadone is used for both short-term pain relief and to stop cravings. When taking it, patients usually experience pain relief anywhere from 4-8 hours. However, it’s ability to cut cravings for stronger drug like heroin is a key reason it is used in detox and drug treatment programs. In fact, people who start taking methadone often continue taking it for at least 6 months for up to many years.

Methadone actually blocks the things that make people feel high from drugs like heroin and oxycodone. What is important to note with methadone, however, is that with proper dosages, the person taking methadone should not really feel “high.” Instead, s/he should feel normal and ready to function in the world.

Short-Term Effects

The short-term effects of methadone are similar to heroin, but less intense and longer lasting. Effects can last up to 24 hours, while heroin’s effects last approximately 2-3 hours. The effects of methadone can include the following:

  • Drowsiness.
  • Nausea.
  • Feelings of euphoria.
  • Pain relief.
  • Relaxation.
  • Respiratory depression.
  • Sedation.
  • Vomiting.

Furthermore, full pain relief is usually not attained until 3 to 5 days after you begin dosing. Indeed, the first 3 days on methadone are critical. Doctors are advised to monitor patients closely for respiratory depression, especially within the first 24 to 72 hours and to monitor or lower the dose carefully. Finally, because methadone has a long half-life and is known to be eliminated from the body slowly, risk of overdose exists.

Long-Term Effects

According to the Office of National Drug Control Policy, when methadone is taken under medical supervision, long-term maintenance causes no adverse effects to the heart, lungs, liver, kidneys, bones, blood, brain, or other vital body organs. Rather, the long-term effects can be positive. The long-term effects of methadone treatment include positive outcomes like:

  • Better physical appearance.
  • Better mood.
  • Feeling healthy.
  • Decreased incidents of blood born diseases like HIV or HCV infection.
  • Improved appetite and weight gain.
  • Increased social, work, and employment contriutions.
  • Reduced cravings.
  • Reduced drug use for heroin or other opiates.

However, the drug can cause discomfort. In this study, methadone maintenance patients reported jerk movement, frequent urination, dark urine and urinary retention, dizziness, headache and body pain when they were on methadone. [3] Long-term use has also been associated with impaired judgment, and it can lead to heart problems, just like other opiates. Other common long-term effects include:

  • Constipation.
  • Impaired judgment.
  • Lowered sexual desire.
  • Respiratory problems.
  • Skin lesions.

Side Effects of Methadone

Side effects should be taken seriously, as some of them may indicate an emergency. Tell your doctor if any of these symptoms are severe or do not go away:
Difficulty falling asleep or staying asleep.

  • Difficulty urinating.
  • Dry mouth.
  • Flushing.
  • Headache.
  • Mood changes.
  • Sore tongue.
  • Stomach pain.
  • Vision problems.
  • Weight gain.

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical help:

  • Agitation.
  • Confusion.
  • Decreased sexual desire.
  • Difficulty breathing or swallowing.
  • Extreme drowsiness.
  • Fast heartbeat.
  • Fever.
  • Hallucinations (seeing things or hearing voices that do not exist).
  • Hives.
  • Hoarseness.
  • Inability to get or keep an erection.
  • Irregular menstruation.
  • Itching.
  • Loss of coordination.
  • Nausea, vomiting, loss of appetite, weakness, or dizziness.
  • Nausea, vomiting, or diarrhea.
  • Rash.
  • Seizures.
  • Severe muscle stiffness or twitching.
  • Shivering.
  • Sweating.
  • Swelling of the eyes, face, mouth, tongue, or throat.

Methadone Risks

Methadone, as with many of the other most addictive prescription medications, is a potent Schedule II opioid pain medication. This means methadone addiction a very real possibility.

Overdose from methadone is a major concern and continues to be problematic in the U.S. Methadone overdoses are associated with severe respiratory depression, decreases in heart rate and blood pressure, coma, and death. In some instances, people who use other narcotics (such as heroin or OxyContin) turn to methadone because of its increasing availability. Methadone, however, does not produce the euphoric rush associated with those other drugs; thus, these users often consume dangerously large quantities of methadone in a vain attempt to attain the desired effect.

According to the CDC, methadone continues to account for nearly one in four prescription opioid-related deaths. In fact, we’ve seen the overall prescription opioid overdose death rate (involving natural and semisynthetic opioids and methadone) increase 300%, between 1999 and 2014…experts think that methadone prescribed for pain as well as for maintenance therapy is at the heart of this trend. [4] [5]

Misuse of methadone can also lead to problems. Because the effects are relatively similar to that of other opiates, it can be addictive on its own, even as it is used in the treatment of heroin dependence. Furthermore, mixing methadone with other substances that slow the body like alcohol and benzodiazepines increases the risk of breathing problems and death.

People who abuse methadone risk becoming tolerant (the body gets used to the presence of the drug, and needs higher doses of methadone), and physically dependent on the drug. When these persons stop using the drug they may experience withdrawal symptoms including muscle tremors, nausea, diarrhea, vomiting, and abdominal cramps.

Abuse and Legal Issues

Is abusing methadone illegal?

Yes, abusing methadone is illegal. Methadone, as we said above, is a Schedule II substance under the Controlled Substances Act. Schedule II drugs. Abuse of these drugs may lead to severe psychological or physical dependence. Abuse is considered:

  • Taking methadone without a prescription.
  • Taking methadone other than prescribed.
  • Trying to alter methadone and snort, inject, or administer it to get high.

Drugs to Avoid

If you’re taking other medications, notify your prescribing doctor immediately. When mixed with other drugs, the chemicals can be dangerous to you. Why?
Methadone is metabolized by cytochrome P450 enzymes in the liver and selectively binds to mu opioid receptors. Medicinal products metabolized by these enzymes or competitors of mu receptors can modify the action of methadone, either decreasing it or increasing it, in the latter case it could be risky or even lacking for the person if it is not taken into consideration. These substances include:

Anti-epilepsy drugs, like phenytoin, that reduces blood levels of methadone by approximately 50% in 3 to 4 days. Other inducers of antiepileptic enzymes (phenobarbital, carbamazepine) increase the metabolism of methadone.

Anti-tubular drugs, like rifampicin, that reduces plasma levels of metadome, so the dose should be adapted. Rifabutin does not affect the kinetics of methadone.

Anti-viral drugs, like zidovudine, which in the presence of methadone increases the risk of undesirable effects.

Benzodiazepines mixed with methadone can be fatal due to respiratory depression.

Brupeofen is a methadone agonist in doses of 1 and 2 mg.

Chronic alcoholism reduces the area under the curve, while acute alcoholism increases it, enhancing the effects of methadone.

Fluvoxamine causes plasma levels of methadone increase from 20 to 100%.

Pure morphine agonists increase the risk of respiratory depression, while partial agonists promote the development of withdrawal symptoms.

Signs of Overdose

It is important to recognize the signs of methadone abuse as early as possible to prevent an addiction from developing. Likewise, you’ll need to recognize and treat signs of an overdose. Call 9-1-1 if you notice any of the following.

Symptoms of overdose may include the following:

  • Cool, clammy, or blue skin.
  • Drowsiness.
  • Limp muscles.
  • Loss of consciousness (coma).
  • Slow or shallow breathing.
  • Small, pinpoint pupils (black circles in the center of the eyes).

While the person are taking methadone, they may be told to always have a rescue medication called naloxone available at home or in your office. Naloxone is used to reverse the life-threatening effects of an overdose. It works by blocking the effects of opiates to relieve dangerous symptoms caused by high levels of opiates in the blood. [6]

Your Questions

Have you experienced any of these side effects?  What other side effects have you heard about from people who are currently taking methadone?  If you have any more questions about the methadone side effects, please leave your questions here. We try to respond to all legitimate questions with personal and prompt replies.

Reference Sources: [1] MEDLINEPLUS: Methadone
[2] DUKE UNIVERSITY: Narcotics Analgesics
[3] NCBI: Physical Effects of Methadone Maintenance Treatment from the Standpoint of Clients
[4] CDC: Methadone Prescribing and Overdose and the Association with Medicaid Preferred Drug List Policies — United States, 2007–2014
[5] CDC: Trends in Methadone Distribution for Pain Treatment, Methadone Diversion, and Overdose Deaths — United States, 2002–2014
[6] DRUGABUSE: Opioid Overdose Reversal with Naloxone
HHS Texas: Onset, Peak, And Duration Of Common Pain Medicines
NCBI: Drug Interactions With Methadone
NCBI: Use Of Methadone
NDIC: Methadone Fast Facts
SAMHSA: Methadone
TOXNET: Methadone
NCBI: Long-Term Effects Of Methadone Maintenance Treatment With Different Psychosocial Intervention Models
About the author
Jana Burson M.D. is board-certified in Internal medicine, and certified by the American Board of Addiction Medicine. After practicing primary care for many years, she became interested in the treatment of addiction. For the last six years, her practice has focused exclusively on Addiction Medicine. She has written a book about prescription pain pill addiction: "Pain Pill Addiction: Prescription for Hope." Also see Dr. Burson's blog here.
Medical Reviewers
Dr. Dili Gonzalez, M.D. is a general surgeon practicing women's focused medici...
Dr. Goecke is a medical doctor and general surgeon with personal experience of...

All of the information on this page has been reviewed and verified by a licensed medical professional.


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  1. Hello, my name is Brittany and I came to this site while trying to find info on side effects of Methadone but didn’t find what I’m looking for. 3 days ago my pain doctor switched me from Oxycotin and Oxycodone that I’ve been on for 8 months, to Methadone – for a severe pain condition. I’ve been doing fine on it and feeling fine with the switch, I just completely stopped the two Oxy prescriptions I was on and began the Methadone, as my doctor said that I shouldn’t have problems switching. But I noticed the first night I took the Methadone, my hands began getting shaky, and now that it’s been three days, they’re still shaky, especially at night after taking my 3rd dose of the day and taking my nightly medications along with it. It’s becoming very annoying because at night they get so shaky it’s hard for me to type on my phone or anything like that, and of course I am worried about it because I don’t know if this is something indicative of a severe side effect. Is this something that is normal when starting this medication and goes away with time, or is it a sign of more? Please let me know what you know about this ASAP, as I’m really starting to worry. And it’s the weekend so I can’t call my pain doctor to ask. Thank you!

  2. I have been on methadone for 21years. I realize I’m on a high dose, 150 mg . I was on 200 , but last year the clinic doctor required everyone over 150 mg to take a peak and trough test. Every single patient on a dose higher than 150 had their dose reduced. Everyone, how can a test be given to a large group of people and every single one need a reduction in dosage??

  3. I have been on methadone for almost 3 years. Here in the past 3 months I have developed some bad stomach pain. I am also experiencing constapation, and vomiting. What can I do about this? I am currently taking bismuth, tums, and famonadine. At times it is so bad I end up in the bathroom for a long ass time.


  5. Hello I am curious to know if taking methadone can leave you with a film like substance in your mouth. I went to a walk in clinic and was seen by a NP, and was told oh you have thrush. The NP gave me a perscription for Nystatin and said this should take care of it. Well I stiil have this problem going on in my mouth, and in night time and when I first get up seems to be the worst. Im just wondering if this is something that goes along with taking the methadone, or if maybe I have something else going on.

  6. Hi I’ve been in methadone for 8 years and been stable on 35 for two years coming from 150 and now I’ve been losing my dose I went from 35 to 20 in three days and I’m getting severe headaches like a band around my head of pressure, is that withdrawals?

  7. e again I’m vegetarian ) I had painful swelling in my legs before treatment that has returned. I flew several times on an overseas flight and my left leg especially had swollen up so bad I couldn’t fit my shoes, that I was embarrassed to wear a skirt, and could barely walk on my beloved trip, ….

    I’m always hurting.

    Try to kick on your own, and don’t take this for pain. I was wanting to die many times the first year it teo I was sick, and I feel so OLD. It’s nog worth it .

  8. I have started taking methadone to get away from opiates and was doing good till I realized one morning I was swelling up then I started itching a lot. I don’t want to be taken off the methadone cause it’s working great what do I do in the case ? Is there another medication that may help if taken with the methadone?

  9. Hiya I’ve just started on 60ml ov meth and feel great, I tried subutex but that put me into an instant rattle and put me in the worst pain ever, ime from Mansfield in England x

  10. I’ve been tapering off methadone for three months. 1mg every two weeks and having noticed nothing the doc said 2mg a week would be ok. The first two decreases were felt but nothing major, sniffly nose, sneezing, etc. However the most recent time I have been fully sick as if in full withdrawal twice and it’s random. I can’t get this horrific smell out of my nose, the same one you get after missing two or three days on a holiday weekend, and I noted when reading this and many others I have had 75% of the major side effects since I began methadone. It states above seem medical help immediately if you have the symptoms but I’ve had most of them the whole 3 years CLEAN from pills and on methadone. I’m worried I’ll be on methadone forever. I can’t continue randomly getting sick like this as today when it happened I was slowing down on I70 and had just about killed myself and everyone around me when the full body sweat, sneezing, and violently throwing up and dry heaving. I’m worried I should’ve been more self aware at the beginning but getting my life on track and being sober was a first fir me then and not something I wanted or was willing to risk losing so my mind wasn’t worried about it. Maybe I wasn’t dead and figured I easily could be not sober so the lesser of the two evils consumed my mind. I’m very worried-I am a single mommy, 4 babies, no parents no family, not even a brother or aunt, and worry desperately for my children’s unknown future due to my inability to focus enough to have realized this. Three years and now I look this up?!? I guess I was scared the rumors of methadone being life long would be realized if I looked into methadone. I just want off. Before it helped, now it’s an expensive unnecessary burden.

    1. Hi Sally. Maybe your doctor needs to adjust the daily Methadone dosage. I suggest that you consult with him/her to help you plan a slower tapering schedule.

  11. I’ve been on methadone for 2 years. I have severe joint pain and skin legions. They tell me it is not the methadone. Is it? I also nod out a lot and hallucinate.

    1. Hi Gwendolyn. I suggest that you consult with your doctor to run some tests about your hallucinations.

  12. My doctor had me on 80mg.of methadone for severe pain from 2004 until my last dosage on June 3,2018.He retired and now I have a new pain doctor that does not prescribe methadone but now has me taking Percocet 10mg.1 tablet four times a day.I also take norvasc 10mg one a day.l have also been prescribed Alprazolam 1mg.tablets,1 four times a day since 2004 for severe anxiety and panic attacks.I continue the Alprazolam.No methadone since 6-3-18,but it’s still in my urine as of 7-23-18.Please tell me how it can still be positive?

  13. its amazing how wrong doctors can be sometime…I know from personal experience and education that methadone DOES NOT BLOCK OTHER OPIATES. I=f you take heroin while on methadone you CAN OVERDOSE.If you take methadone daily your tolerance will increase greatly and the amount of heroin you would need to take to get “high” increases. Im guessing this where this false BLOCKING opinion comes from. If you take enough drugs you will get “high” but chances of overdose are great.The miss conception that you cant take pain meds while on methadone is just not true’ Doctors just have to give you more that most people for it to “break throu”. If done responsibly and under supervision it CAN BE DONE. Its clear this doctor has NO experience in methadone treatment and is repeating garbage pick up from other uninformed people. The real danger is when uninformed doctors don’t help their patients very real pain issues because of stigmas and rumors and those people look elsewhere for relief. Doctors were ENORMISLY IRESPONSIBLE in their opiate prescriptions writing in the past . (People with a bruised shins do not need oxycodone) Now people who truly need help are affected. Unfortunately 90 percent of doctors have NO REAL concept of what true Chronic pain is because they have never experienced it and for self preservation and peer opinions will send away someone truly suffering.

  14. To Lisa: This is a shot in the dark, but is your friend perhaps taking any other prescription or herbal medications? Some medicines are cyp3a4 inducers, which when taken with methadone, which is primarily metabolized through this mechanism, can greatly reduce the amount of methadone in the body, simply put.

  15. Hi can someone help me please,my friend is on a Methadone program been on it for about 10 weeks now 80mil a day but the last 2 weeks she hasn’t been feeling well felling sick hollow sweating really bad and clammy flushes and then feeling cold can’t be bothered to do anything could it be the Methadone thanks

  16. I was on methadone for almost 5 years, it very much saved my life, but I now have bin off it for 11 days, with less side effects then expected i feel very lucky, lots of praying!, my biggest issues is getting a full nights sleep and the belly cramps, hoping this goes away.
    i wish everyone the best and hope if you are trying to become free from the daily methadone does that it works for you!

  17. Hi all I am talk texting so please bear with me if there are any misspellings Etc. I myself have been addicted to methadone through the methadone clinic for 13 years. For me it is hell. In my opinion it should be illegal other than for those who cannot take other pain medications and or in excruciating pain and or dying. Or I think it would be okay for a 21 day detox if you are stuck on heroin etcetera. My side effects once I got up to 20 mg and above have been stiffness, weakness, hard to move around loss of appetite lost weight dry mouth dry skin dry hair depression anxiety feeling less than. Lack of Interest my drive is gone I have no drive or any passion to do anything like I used to when I was clean. Short-term memory is completely gone. Teeth are breaking off. But one of the worst side effects from me is I got OCD I got a picking Disorder so I have picked myself for 13 years and my body is completely scarred all over and the thought of kicking methadone cold turkey so bad I’d rather the dead. I tried to taper down and get off that way but the withdrawal symptoms were 10 times worse than kicking heroin to me. I have been tapering down 1mg at a time at the clinic this time I am down to 39 mg. The doctor is the one that told me to do it that way and it has been working but now the clinic says I can’t do that their policy is not to go down one milligram at a time it has to be 5 at a time. Well that’s too much because I my job I work 8 to 10 hours a day non-stop and I have to be able to function properly so to me that is too much I’m going to feel that emotionally and physically. I think they just don’t want me off so they can keep getting their five hundred and something dollars every month from me. Florida is a non Medicaid State so Medicaid does not pay for it in fact I can’t even get on Medicaid. I have been researching different Avenues to help me in the end to ease my withdrawal symptoms. Kratom is legal and that supposed to help a lot maybe some CBD oil. And other over-the-counter stuff you know for nausea and diarrhea, excetera but cuz I have felt days of the withdrawals before it’s almost a phobia there now and I want off so bad but I’m also so scared I don’t know what to do. My biggest fear is that I can get off and because my health is so bad now I don’t know if I’m ever going to regain any Health back or get any of my brain back. Thank everyone for your comments and for the information on what can help with withdrawals I appreciate it with everything I have. The one thing I do know about methadone is it affects every individual I’ve known a lot of people on it and putting my ex-husband who has passed away from hepatitis C and but there are some similar symptoms as well. The number one symptom that I noticed everyone is they’re not the same person they might think they are but they’re not!

  18. I’m a newbie to methadone. Just started with a clinic. I can say it has been like night and day. I was on percocet from a pain clinic for 5 to 6 years
    Kind of just living in a fog . Wanted off so started this process. I have had a better quality of life and enjoy things I didn’t do before. I just have one question. I have just in the last 3 days had spells of crying and just feeling helpless. Don’t know if it’s normal or if I should get concerned. I hope its just a phase. Because this is really helping my life.

  19. I took methadone for pain pain only I’m not a dope attic and all that crap that I hear about methadone in your side effects you just said I never had any that gain weight a dick around my sex a little bit never gave me gain weight never gave me the sweats morphine gave me sweats and crap like that when I tried me on morphine I didn’t want to take that no more but I hear so much bullshit about these pills and all the crap in the doctors won’t give me no reason to rhymes why they won’t give them to me because no I want to give them to me and I’ve been on them for 1518 years and I’ve never had a problem now I’m down to a half five megs every three days thanks to the lousy fucking doctors I’m trying to get off of them to see if I can stay off of them and live with minimal pain that I have but that third day my body feels weird is that going to go away after a while or do I need to take something else and yes I am exercising and I’m 56 years old

  20. I was diagnosed with Emphysema. My symptoms included shortness of breath, dizziness, lack of oxygen to all body parts, numbness of fingers, no energy, no appetite, fatigue, and bloodshot eyes. I was living at a place that has mold and mildew in the air conditioning unit. I also smoked a pack a day for 20 years. The Pulmonologist started me on Spiriva and Advair plus nose sprays, to reduce symptoms and slow down progression but I could not tolerate them for long due to severe side effects. I decided to adopt a more natural approach and started on Emphysema Disease Natural formula from THE HERBAL GARDENS, the Emphysema natural formula immensely helped my condition, it reversed my Emphysema. My severe shortness of breath, dry cough, low energy, fatigue, chest tightness and others gradually disappeared. Visit THE HERBAL GARDENS via their official web-site This Emphysema treatment has improved the quality of my life greatly, i breath much better and feel comfortable doing so. Since the procedure I enjoy walking the dog for my daily exercise. DON’T GIVE UP HOPE!!!

  21. I don’t use terms like addiction in my case. Sure I depend on narcotics, just like I depend on insulin for diabetes. I’m sure people abuse them, I’m sure they know the dangers. If they want to kill themselves then ask god to forgive them and let it go. True addicts? There are programs out there. True addicts only want one thing, and that’s to die trying for cheap thrills. So let them. They are the reason that people who really need them for pain, have to go through pure hell to have relief. So many needed tax dollars wasted on addicts who really just have a death wish. I see things two sided. Dependency and addiction, is the later really a disease? A self inflicted one, at best. There are temptations in life. Soon I’m sure temptations will all be termed diseases. And I do have a living heart. So give the addicts 1 chance to live again, then waste no more time and money on them. Give it to the people that have to depend on high risk meds to live again, if only for a while. I’m a little put out by addicts anyway. They steal, pillage, even kill, because they plain don’t want to deal with real, every day normal life. its too hard and boring for the little bity babies. You know who you are And let the government take care of this problem, and it will never end, cause ” we the people” will have no guns to protect our home and families from the darn zombies. Ok enough. I’m sounding like Ted Nugent now! Clean And sober, all his life and still going at 68 yrs old. A moment of silence for uncle Ted, Please! 6,000 and some concerts. Unreal !!!

  22. Before this chronic pain, I was high on life. Then life turned against me until all I could think about was pain and not being able to participate in the things I love to do. methadone made my life worth living again. I don’t like the thought of taking narcotics, especially after critics made such a filthy word of them. if I were offered another course of treatment that worked, id jump on it. I’m on other maintenance meds that far out weigh any negative side effects of methadone. it will clog your receptors in your brain after a while. Then you must ez off or cut dosage back for awhile. then resume taking them if need be. After 10 – 12 yrs on methadone, I have no serious adverse effects. They are still efffective

  23. methadone probably saved me a life of unproductive pure misery. Ive been prescribed methadone for at least 10 yrs, through pain management. Diagnosed with central pain syndrome, via an intra- dural spinal cord tumor( lipoma type), and its secondary effect, which is very slowly crippling and now very painful. Never had to increase dosage. I have an ekg every year because long term use may cause a heart condition. with a spstic gait, methadone actually helps me ambulate better. it was a last resort effort to control pain. a long acting maintenance medication.

  24. When I was an active heroin user for 21yrs I always brushed my teeth and floosed them everyday. If I had to swipe the toothbrush and toothpaste. Now Im on 110mgs of methadone on and off for 15 years. If need be Ive resigned to be a lifer. I am still diligent to brushing my teeth 3x’s a day and flossing 2 to 3’s a day. I just turned 50 yrs old. My teeth are breaking off at the gum line, chipping, breaking in half and the enamel is chipping off. You can not tell me this is not from methadone. It is quite distressing and scary. They are all going at once. It’s like the nightmares I had as a teenager. If it isnt, PLEASE EXPLAIN HOW AND WHY THIS IS HAPPENING. THANK YOU FOR READING AND FOR YOUR TIME. BLESSED TO BE ALIVE!! ❤ PEACE AND LOVE!!

  25. I’m in a bit of a jam, in fact, it’s a hell of a jam now. I was struck by a speeding car in 1977, both legs and pelvis/lower back were fractured. My skull and jaw were fractured. Numerous surgeries on knees and pelvis, adding & removing hardware that was surgically implanted over the decades. They started me out on two Percadon a day to treat the chronic pain that resulted. That later was replaced by Percocet. In 1985, after a menosectomy of my left knee, my dependence to narcotic anslgesics, particularily oxycodone in some form and dose,began. OxyContin was brought in the picture. The big pharma outfit Purdue was saying that their new form of oxycodone delivery was “non-abusive”…well, maybe not exactly that, but close. I knew how addictive it was, I took it AS PRESCRIBED for over ten years by then. Who’re they (Purdue) trying to kid I thought. Anyhow, as time went by, surgery after surgery, until both knbees were totally replaced, I was on 100 microgram per hour Fentanyl transdermally…patches of course. You see, I actually wore the patch, and just one, and I never even contemplated smoking it on aluminum foil. That has to be the stupidest thing I’ve ever heard of for a plentitude of reasons. Now, to make a long story…less long, I was dumped by my doctor of 15 years, only to have to line up at the methadone/suboxone clinic. Don’t get me wrong, the OATC is fantastic, saves lives, truly compassionate to folks with what they refer to as a disease, rather than a scourge to society. Thing is, I took this shit for PAIN, actual physical pain & suffering. They made me feel like a piece of shit…a bad seed…they still do. Is it right, or fair, to punish me in this way? Force me to take a drug that has side effects I really cannot get used to…it’s difficult for me to function normally on the alternative to oxycodone. I’ve been taking oxycodone as prescribed by a physician/surgeon for three decades plus…now I must line up like a soup kitchen bum for stuff that makes me sweat profusely, sleep too much, gain weight excessively, lazy, ZERO sex drive,…I just don’t get it. It’s for the best Gerry they say. The best? I still can buy OxyNeo from the street at exorborant prices…but should I? The system really fuktup with this one, and I’m in the eye of the tornadoe.

  26. I started methadone ⚂ months ago and about one to two weeks later I started having a lot of breathing problems. I told them I had copd and azthma. They know they also know breathing is not been good for me. And they do t care. I was up to 85 mg and now downs to 70 mg. I’m cutting down slowly. And I feel okay on the opiod wd I’m not having by dropping down already.

  27. I need to know if lamictal will take the methadone out of my system, ? Plz if anybody can help please message me back I need to know this thank you bye.

  28. I was first prescribed Percodan after knee surgery in 1985, then after continuous surgeries on my legs and knees, I was put on Percocet…It was apparently less hard on your stomach. Then the “completely safe & non-addictive” OxyContin…after decades of up to 300 mg per day of OxyContin, Its changed to Fentanyl patches ,100 microgram patches. After the shit-storm of oxycodone/fentanyl subsided, my doctor cut me off 25 mg Fentanyl patches COLD TURKEY. She did this last year too…when I was on 50 micrograms fentanyl patches. I want to kill her…I said I want to, I never said I will.Now, I line up at the methadone clinic every fukin day like a Jew lining up for a shower in 1940’s Auschwitz with my medical marijuana prescription to replace the narcotic analgesics. The methadone gives me many unwanted side effects, like weight gain, laziness, retarded sweating, no sex drive, and who knows what else. One question here…WTF?

  29. I reacently had oral surgery and am in the middle of a short term detox using methadone to get off pain Ned’s. Can methadone cause face swelling?

  30. Are the Doctors and pharmacutical company’s and anyone else that has made a fortune by getting people addicted to this stuff that now they are saying it’s harmful to your health will they be held liable any other thing that has done this people have been able to sue those that are one of their ducking monkeys that has supported to their cause anyone else feel this way

  31. To April: You very well could be suffering from opitate neurotoxicity! What you are describing sounds like myclonus, which is a common symptom of opiate neurotoxicity. You need to get checked out girl!

  32. Methdone has made me start having body jerks to the point where I’m not sleeping. The doctor has never told me about the side effects or given me any warning about thus drug and the jerks are bad. There is no warning label on my medicine bottles about thus either.

  33. My name is Michelle and I am a 36 year old female and I have been on liquid methadone for about 13 years now at a stable dose of 235mg a day. I have been on this dose for about 4 years now. I started noticing nausea about 7 to 8 years ago but at first it wasn’t bad. I would only get nauseous about once a month. Well as the years went on it gradually got worse. Now after being on methadone for 13 years it has gotten really bad. I am nauseous every day sometimes all day. My stomach cramps when I eat anything and I have no appetite most of the time. I also got these really bad hot flashes when I am sick. Before I went to the doctor a few months ago it was so bad that at times I was throwing up. I started thinking I had ulcers from all the past years of taking pain meds (Before I got on the methadone, which was the reason I got on methadone as pain management.) Well after seeing Dr after Dr I finally got a endoscopy to look at my stomach. The stomach Dr said I didn’t have ulcers but that my stomach was really inflamed due to stomach disease but then told me no more about it and wanted to get my gallbladder looked at. So doing my own research I read that certain medications like anti inflammatorys can cause stomach inflammation and that can lead to ulcers and bleeding. It also said that stomach inflammation will make u very nauseous and sick to your a stomach and cause vomiting. So I am wondering if taking methadone for 13 years has over time made my stomach inflamed which is what is causing me to be so sick. The Dr has Me on Omeprazole for the acid and Misoprostol which is a ulcer medication and zofran for nausea. The zofran helps alot and I haven’t thrown up since taking zofran. But my question is Do u think the methadone could make my stomach inflamed? Have u or anyone else ever heard of that before? I need answers and it seems these medicade Drs are not gonna figure it out. I would really appreciate any help I can get. Thank you.

  34. My mom takes methadone. She has gained so much weight, her knowledge has decreased, and she walks around sleeping standing up….I hate it. Is this normal? She falls asleep driving…some nights she doesn’t sleep at all. Is she supposed to take the whole dose at once or a little bit throughout the day?

    1. Hi Katlyn. These side effects are serious. I suggest that your mother consults with her doctor about dose adjustment.

  35. I have been on methadone for almost 100days. For the first like85-90days I continued to use heroin. I recently quit the heroin. I’ve been feeling light headed, like I’m going to faint, weak in the arms and legs, and weird warm feeling. These come and go. It’s this from the methadone? I just started having these symptoms like a week ago!

    1. Hi Lisa. It seems to me that these are heroin withdrawal symptoms. I suggest that you consult with your doctor about methadone dosage.

  36. I’m on 180mg of methadone…I would like to come off as of right now I do experience my body aches when I workout. I can weight lift for two weeks or two months the soreness is the same. I know as a bodybuilding over the years if I was to take some time off for my workouts when it came time to return I would feel some soreness the first week back from bodybuilding this was before my methadone treatment. So I been on the methadone treatment for almost 3years now when I lift weights now I can’t believe the pain my muscles are enduring I been trying to get over this intense pain in my body when I working out is this because the methadone has got into my bones and the soreness know matter how long I train for. Could you explain why please… thank you

  37. A cop told me one time, “well methadone is just legal heroin”…..I replied to him with malice,”no it is not and you need to be reeducated.”

  38. hi ive had sexual disfunction problems for the last 15 yrs which are horrible to try & live with,ive avidly on a daily basis try to fix,i do believe the main culprit of my sexual disfunction is my left sided varicocele since my teenage days bearing in mind I’m now 51 yrs old,im in a big dilemma as I have lost all my excess body weight,i eat a testosterone friendly diet ie good fats,like I said I’m in a dilemma as I’m trying to find the cause of my sexual disfunction,on research I 100 % believe its mainly due to my varicocele as my testosterone cannot gain access to my kidneys to be diluted then processed through the gland endrocine system because of gravity it has no other way to travel by the means of gravity other than to my prostate gland hence enlarging it,i only know testosterone enlarges your prostate gland as reluctantly I tried trt many years ago briefly for about 5 – 7 days & it enlarged my prostate gland hence making my urine trips to the toilet more frequently,after a lot of research I’m 100 % confident an operation called selective occlusion of venous drainage valves ie novel new treatment is the only possible answer to eradicate the route of the problems,im at my wits ends as the endrocologists just seem that trt is the answer but truth being told it makes my urinating more frequent & dose nothing for enhancing my lobido & also shuts down my natural production all being it very very low to the extent that it feels that ive been castrated,could anyone put myself forward for the day operation ie occlusion of venous drainage valves, many thanx for your support & help

  39. I take methadone and recently a mass was found in my liver after an ultrasound. Do we really know everything about the effects of methadone? I’m a concerned methadone Client.

  40. What does earlier n earlier n earlier times “have to” get to clinic mean?A year ago, relapsed on 40….stopped using increased to 65 n all well until a few months ago…then went from 10 am to now 6 am have to be at clinic. Always I’ll be fire 1 hr post dosing. .

  41. Hello, I’ve been addicted to pain medication for about 20 years. aways pain pills and ending the last year with 30-90mg of oxy a day. I also take bento 1 -3 mg daily. I recently got on methadone for treatment. I started out on 25mg but still continued to use. At 25 I felt great thought soon I’d quit and all would work out. Then I felt a strong desire to drink. I couldn’t not. I was having major problems. Then I realized how scary that was and quickly cut back to two drinks a day max no more Roxy and as little benzo as possible, like 1 a day in the late evening. My anxiety is through the roof. I stay up all night feeling crazy and wanting to go to the hospital. I read so much on methadone, that it makes me scared and crazy. After I dose I get relief and pass out. Its all I can do to get out of bed. My anxiety ramps up and I want to drink to kill it, or to see if something will help. so basically I get tired the first few hours then I’m crazy with anxiety and agitation all night until 4-5:30 am. I hate the way I feel. I put in to go up on my meds to see if i’m in withdraws, but maybe my dose is too high, and thats why? I’m feeling like i have the flu and anxious but the same time headaches and tired and can barely stay awake. I feel like I have nobody to talk to. I used to take methadone in the pill form but with Roxy and it was perfect, I guess my body just wants that?
    pp help -z

  42. I have been on MMT program, since June. It has save my life,for real. Nothing work started in rehash age 28 now 60. I wish I knew about this sooner,but better late than never.I am gaining weight and I am getting up every 1 hr. at night. I am sneezing still and very ache. Is this normal I am at 80mgs. Can anyone help me.

  43. ive been on daily methadone addiction for nearly 20 yrs,i wake up with no errections,ive no lobida atall,ive got bph,varicoceles on my left sided testicle,can you supply me with any help as I have researched daily for the last 10 years for results to regain my sexual function with no success,i can only ejaculate a tiny amount of semen on average every 2 months,i need help desperately of which my gp prescribed myself with testosterone replacement patches as I was not keen on but took them for several days & it only made my bph worse & had no effect on my lobido? many thanx john

  44. I’ve been on 60mg.of methadone for 12 years now. I’ve been taking the pill form, 2/10mg.x 3= 6 per day totaling 60mg. after being on liquid , 60mg. for 11 of those years… Also prescribed 5mg. oxycodone for breakthrough pain. One every 6-8 hours as needed for pain. Btw.. I’m on these for pain mgmt. under a Doctors care. (* started at a Methadone clinic, and switched to Pain Mgmt Center. ) I guess Methadone works very well with chronic pain management. I have gained weight, and am constipated on occasion. I may want to switch over to something other than methadone, if possible… This is because a newer Dr. doesn’t like prescribing methadone. (* and now I’m fearing the unknown, and getting anxiety and a little depressed because if I have to go elsewhere, I’m not sure they’ll take my insurance, etc…)

  45. What ever people say or how bad methadone sides effect, I just don’t care..from now on.. The important thing to me and other people must to beleiv :
    MY LIFE NOW IS MUCH BETTER THAN MY PAST LIFE (BEFORE TAKE METHADONE). This is my true experiences, Methadone has good reason for healthier life. TQ

  46. My son was weaned from Methadone last year after being on it for 3 years. He no longer has cravings for any drugs and is back in college and doing well. My concern now is he continues to have sugar cravings and is 50 lbs overweight. He has tried to control his appetite but has been unsuccessful. I’d rather have him overweight then on drugs but he is unhappy with his appearance. Any suggestions? Thank you!

  47. Yes i have noticed while on only methadone strictly without anything else including illicit that i have gained considerable amount of weight, lost a considerable amount of activity level, and lost a great amount of drive. I now have a problem losing the weight because of my metabolism being so low and my adrenal glands not pumping as usual. Sexually erections will come and go during the act. The fact that now i have supplementd my diet with CLENBUTEROL and CYTOMEL or T3 , my spunk and tenacity is back i have lost alot of weight like i should and my manhood has regained top.

  48. My fiance is currently on 60 milligrams a day of methadone I have concerns because sometimes her body functions and emotions take over without her moving them .she sometimes stands in the kitchen her eyes are rolling around in her head. neck movements and head are uncontrollable she’s up and down on her toes. I guess what I’m asking is long term use of methadone does it affect and change or alter the brain or nervous system of the body.

  49. my son just started methadone TX for oxi addition (4 days TX so far) his first day at clinic 30mg and then up to 40mg these last 3 days. He is nodding out. His oxi addition was 30 mg x 1 to 3 or 4 times a day (smoking them) And some days he goes a day or two without oxi if he cannot get them. He drinks beer still and said he would smoke a pill if he got one. What I have been reading on line is that there is a danger of overdosing. He has asthma as well. My 1st question is : should he remain on 30 mg methadone to keep tolorence low for this treatment. I have been trying to urge him to go to 12 step program as well…he does not see the need. He is 25 yr old been using opiates of any sort for 10 yrs and is bi polor. Just started lithium 3 per day. He has a high tolorance for oxi but I think it is a mental need as well. He does go through the usual physical withdrawl symptoms nausa, sweats, bowel discomfort and is unable to sleep without oxi.

  50. That is crazy I’ve experienced every single side effect except weight gain and sexual dysfunction wow but still this article was spot on thanks!

  51. I’ve heard a lot of talk about ur sex drive and it declines! However, since I’ve started the methadone clinici my sex drive has been better!! How is that???

  52. After reading most of these replies I have come to a common conclusion; METHADONE IS BAD FOR YOU!!!. I am FAT (255lbs) and should be 195lbs. My testosterone level was 7 and should be 200. I sleep most of the day (and night) because I feel overly sedated. My breathing is horrible (shallow and panicky) even though I quit smoking cigarettes over a month ago. My wrists feel weak and shaky I was on 65mgs a day and now I’m on a “blind taper” dropping 2mgs a week. I’m down to 55mgs but haven’t felt better yet. This has been the worse medicine I have been on in my entire life. OK! So it’s better than sniffing heroin but, I can’t wait to be completely off ALL opiates. I want my energy and libido back. I am 61 yo and I am not ready to cash in just yet. I hope this helps someone out there in Methadone Land! .

  53. I have been on a Methadone program since October 2014. This has been the worse 8 months of my life. I sleep half the day away. My wrists feel weak and my hands shake. Even though I quit smoking cigarettes a month ago, my breathing is horrible. I take breathing medicine but I’m sure the Methadone is the cause for the “panic like” breathing feeling. Even though I have changed my diet, I can’t seem to lose any weight. I weigh 255 and should be at around 195. My Testosterone level was checked two months ago and it was 7! It should be at around 200 for a man my age. I am now on a “blind taper dose” of Methadone. They have been dropping my dose by 2mgs a week. The reason I looked at this site is because I was concerned about my drinking with Methadone. I have been drinking alcohol since I was 14 so, you can say most of my adult life. I went from beer to rum back in the Fall of 2014. I have been drinking “box wine” now for about 4 months. I recently started drinking these “flavored coolers”. I have found myself becoming overly DRUNK very fast. I don’t normally have “hangovers” but for some reason, today, I feel pretty sick. I can only blame it on the alcohol/methadone mixture from last night. I hope this helps someone out there. I don’t want to stop drinking (I don’t drink and drive) but I do want off the methadone bullshit.

  54. I have suffered from a very very low lobido & sexual disfunction & the cause has to be my 20yr addiction to methadone,even when I tapered down to 20mg a day I still suffered from sexual disfunction,i am very curious when I taper completely of methadone will my lobido eventually come back? MANY THANX FOR THE REPLY

  55. I must admit after 20 years of methadone I have only two side effects, constant sweats and horrible constipation. The sweats are almost unbearable due to the fact that I have become Menopausal. the constipation is so bad that my doctor has triedjust about everything and nothing has worked. My fear is that disgusting constipation will hurt my intestines eventually. in 20 years of using methadone I must admit that I have not had a serious weight gain until the last 5 years. I view this weight gain do to menopause more than methadone. For a long time I was very afraid of the effects of methadone and what it would eventually do to my liver kidneys and Bones.however, after years of use I realize that those fears were unwarranted. as a matter of fact, I think the methadone may have actually saved my life. It certainly brought me back into society and gave me a sense of a desire to live. it gave me my family back my job back, and my home back. But as I stated in my earlier message it’s time for me to get off it now. I think the only problem that I have With methadone itself as a drug as it relates to addictionis that you have such a hard time coming off it. It is three times as difficult to withdraw from as heroin and some people I know even had to go back to heroin in order to get off the methadone. On the other hand, I know people who have actually dosed off going down 5 milligrams to 2 milligrams Per month and say they have not felt any pain.personally, I believe, as a nurse, that no matter how low you goes down the withdrawal symptoms from methadone are of similar severity. I am at the point now where just thinking of drinking one more drop ofmethadone makes me nauseous. every day after I drink my dose I actually have to lay down and settle my stomach. It’s almost as if my system is rejecting it. I no longer feel like I need it.I hope and pray I’m right because I am trying to come off it.

  56. ive seen side effects in my father in law. i do understand hes in pain from his disintegratng back disks but. after he takes his piill he lays down for a bit then hes up and doing things, i think he shouldnt because of his condton. as the meth. wears off hes
    in greater pain, because hes doing things he shouldnt. i am going to talk with his pain mgmt. dr next visit, i know he wont like it but im trying to help him and hes hurting himself. its frustrating.

  57. I have been on methadone and clean for 7 years now and started because of the tolerance build up of other pain killers. I have actually never tried herion. Pain killers were my drug of choice. It all started when I was in a horrible horseback riding accident and now have chronic pain and methadone just works for me. Anyway, I wanted to comment on some of your post and ask a question or two:)

    First, I defiantly have a sweet tooth!! And have gained 40 pounds since being on methadone!!! Also as far as teeth rotting goes, I think it is the methadone that rots teeth but not in the way you think…many prescriptions, mainly liquid methadone contains a lot of sugar so when drinking it and not brushing your teeth right after causes the sugar to get in between the cracks and crevasses in your teeth and cause cavities. Next, I have been with my husband now for over ten years. He doesn’t take methadone but up to the point I started taking methadone we used to have sexual experiences at least 3-4 times a week…now immediatly after I started taking methadone we only have sex, if he’s lucky, once a month!!! And it’s not because I want it…it’s because he asks me and I feels so bad I just do it!!! So I believe the sexual drive plummets for men AND WOMAN!!! Lastly, sweating is a huge issue with me now being on methadone!!! 8 months out of the year if I slightly move around I break a sweat…mainly just on my face…I would kill to have it under my arms, hidden away!!!

    Now finally and most importantly is my Health issue I am conserned about and haven’t found any information on so I don’t know if it’s a methadone side affect or something is wrong with me. Since I started methadone or maybe 6 to a year in, I started to get my period for longer then a week. I am not and haven’t been on birth control or do I have any sort of pain anywhere around there. However, it’s not like a normal period and It’s not heavy at all…just enough to ruin your underwear by days end but really not go through it…so I just use a tampon…ALL THE TIME!! I would say out of 3 months, I have 3-4weeks without bleeding. So if anyone knows about this or can help me that would be great. I have gone to the Gyno and she didn’t see anything wrong with me but I didn’t have the money to get major tests done because I have no insurance:(.

    Thanks to all who read…I hope the 1st part helps you & hopefully someone can help me with the 2nd part:)

  58. My mom has been on this I would say 15 years now, I always considered this to be a bad drug I believe she’s addicted when she don’t have it my dad says she turns evil and starts crying. She has nothing wrong with her I mean no pain I believe she takes it because it makes her feel good. There’s 6 of us so I think she had her hands full and thought she needed a little help (methadone) she started off with vicodine norcos, I think oxys and stayed with methadone. I strongly feel that they didn’t do her any good she looks older then her age, she’s balding, her eyes water all the time, and it seems like her hearing is getting bad. I’m just wandering if she should get help?

  59. hi do you know anybody personally or statistically who has been on methadone for 18 yrs,lately over last 5 yrs my lobido has disappeared,i eat a testosterone friendly diet,ive trebled my testosterone levels to a good average for a 49yr old male,ive tried avidly on a daily basis to try & improve my lobido for last 5 yrs ,but no gains,everything points to my methadone being the culprit,im on 70mg daily,but when I tapistent ,which leads me to the conclusion I must abstain totally from methadoneered down to 20mg daily my lobido was still non existent which leads me to the conclusion I must abstain totally free altogether from the drug to see gains in my lobido,could you advise myself on hard facts about length of time I have to be free from methadone altogether for my lobido to return to normal,ive read it can take months?many thanx john

  60. Methadone has the same symptoms coming off as anything else but last twice as long. Drink lots of alcohol and eat alot the first week it will help alot. You will have hot and cold sweats, restless leg cramps at night. U can use cold packs for your legs it works great. Sweating was the worst for me but after the first week and a half that should fade. I noticed i lost alot of fluid in my face and arms that the methadone was causing. If u have family and they dont know about your addiction you should talk with them, have them help with cooking or kids if u have them. The first week you will have alot of mood swings so try to stay positive. Take lots of showers even if u feel like your dieing lol it will help also get alot of movies. Drink alot of water, the more water u drink a day the faster and better you will feel. Dont give in cause in the first week thats how your gonna feel. Lots of mindpower getting out of the house helps take your mind off it too even if its just a car ride. If your really going to give in take a couple shots of some hard stuff. You will notice in about two weeks your mind is much more clear and you can sort of laugh again. Although your mind will feel great your body has alot of catching up to do so make sure to drink and eat healthy too. Dont worry all the negitive feelings u have are normal and will pass fast. And yes to some people that have asked all addicts feel depressed thats what those things do to everyone that takes them.everyone feels just about the same when they cant get anything or cant find anything . Shit. Dont talk to people that use or sell them, change your number. To stop you must want to stop. If u dont have much of a life these could be why. Best of luck to u all:-)

  61. I have been taking Methadone 10mg x3 daily for 13 months.. 2 months into I began to suffer from extreme edema from my hips to my ankles. Doc prescribed medication, and it began to slowly disappear, and I have not suffered from edema since June. Next, I started Methadone weighing a a very steady 130. (when I say steady, it is because I have been 125-130 lbs for the past 10 years. Never going below or above.) Yesterday, 13 months into my Methadone daily dosing, I was weighed at 152 lbs. I do not eat more than I did before I began Methadone, nor do I eat any less. I eat the same amounts, and the same type of foods. So, really, there isn’t any reason for the weight gain, .it has to be the Methadone causing the unexplained weight gain. Sweating…GEEEEZ….the amount I sweat is ridiculous. It does not matter what temperature it is, I am sweating. I refuse to wear certain shirts now to avoid showing any wet pit marks. How embarrassing! Another side effect, the lack of interest in sex! This one is a real bummer. Since beginning pain medication 6 years ago (Lortab, and Percocet), ANY sexual desire I had disappeared, so, when I began taking Methadone, it really did not register as a side effect because that was already something I had been suffering with for many years, thanks to chronic pain and the medications they make for it. Anyway, Methadone is a wonderful medication for SOME people…works for some, ruins life for others…and that is all there is to say about that part of the discussion.

  62. I was a size 2 at 5″5 weighing 120lbs ( I seem to carry weight easily w/very dense bones. No broken bones…). Within 5 yrs., I weighed 160 lbs. Methadone definitely slows down your metabolism. I know age doesn’t help but, I was 35 at 120. I’m now 42 & am going to apply myself to a program working out. WISH ME LUCK!

  63. Hi Deborah. I’d suggest taking your husband to the doctor’s to determine the best and safest course of action. I can’t give you any solid advise since I don’t know your husband’s full medical chart, but for now it wil be safe to lower the dose. Even if the decreased dose makes him feel better, still see a doctor.

  64. My husband has been on Methadone 5mg tid for 2 weeks. He then was told to increase it to 10mg tid. He has been on the 10mg tid dose for 1 week. He throws up, constipation, and just wants to come off of it. Since it is such a short time of 3 weeks, how can he come off of it safely?

  65. I myself use methadone 2 10 mg tabs Five times a day for pain and I want to know because my right lower leg and ankle has necrosis..Is methadone having an effect on my bones?

  66. I’ve been taking opiates for 15 years after injuring my back…I now take 50 to 70 mlg methadone and oxcodone for breakthru 20 mlg when need the worst of my symptons is weight gain sweats and the worst is the overwhelming tired feeling in the front of my brain and the closing of my eyes really bizarre dreams it works great for my pain and doesn’t get me loaded or high any one else feel this way thank you

  67. Ive been on methadone maintenance for a little over two years now and I can say without a doubt it saved my life. I had tried rehabs, and honestly wanted to stop but my brain and body never adjusted. The cravings and wanting were always there. Its such a relief to be stable and not running around daily for money and drugs.
    My problem now is the sweating. Irs work I always look strange because im always swearing. Anyone have any REALLY GOOD tips?
    I do know that the methadone does something to my histamine in my body. Is there a med or simple solution? Irs pretty serious. Thx

  68. hi could you please inform myself to your knowledge is it my daily methadone addiction that is suppressing my testosterone levels,i have a reading of 100 bearing in mind normal is 500-1200,i have no lobido atall,i have tapered down to 20mg daily but did not notice any changes in lobido,i am back up to 75mlg daily but I wont to taper of completely to see if my testosterone levels increase,i am at my wits ends regarding this issue as I have tried avidly for the last 4 yrs to increase my testosterone with a testosterone friendly diet,high intend=sity interval training.supplements,wearing a blakoe ball zinger nightly with no results atall in the testosterone department which leads me to come to the conclusion I have to eliminate my daily methadone addiction out of my life completely for my testosterone levels to return to normal as I am so depressed with this issue! many thanx for the support John

  69. I was on 4 mg of methadone for a few years for fibromyalgia and other chronic pain. My testosterone was low in June and now. Will it return to normal?

  70. I appreciate this blog, which contains some valuable information. I’m 58, and have been on opioids most of my life, including the week after I was born when they did an operation on my solid esophagus to save me, and then treated me for post-operative pain with morphine and put me in the incubator to see if I would survive (a “1 in 10” chance of survival he told my parents in 1955). While growing-up I often got lung infections and coughs, which got me addicted to opiated cough medicine, which made me feel ‘normal’ (addicts know what I mean). Then I became a pharma-junkie and heroin too. The last 15 years I’ve been on methadone, from a high of 90mg. at first, then 40 mg, for the last ten years. I tried to detox five years ago, but did it too fast and wrong, so I failed. This time I’m doing everything right, and having a much easier time titrating me dose down. I’ve gone down quickly to 10mg, by taking smaller doses at more frequent times (4-6 hours). Now I take 1-2mg. in the morning, and the 7-8 mg. about 3-4 hours before bed. I’m taking melatonin, which is really seeming to help, and may be the reason most cold-turkey methadone patients can’t sleep for a month or more. My thyroid level is suppressed, which is likely what makes me so weak when I detox, so I’m researching how to treat it. My doc gave me two blood tests, and prescribed some “levothyroxine” for my hypothyroidism. I like to go holistic though, so I’m researching holistic treatments. Does that make sense: that the pineal gland is what makes us not be able to sleep, and the thyroid (which effects the adrenal gland) makes us weak? I’m going to add maca root to stabilize my endocrine system, and raise my testosterone level. There are many other herbs I’m experimenting with, after researching them, and considering negative synergistic effects. I also want to uses acupuncture and massage, hot baths, etc. Any thoughts about my hypothydroidism issue during detox? Thanks in advance!

  71. what we need is tips on when your abruptly detoxed in jail, then sent home to cope with Years of Methadone withdrawls. Some people tell me it takes a year to get back to normal, I am going on 3 months & I feel sick as ever. I have other Pain Issues though? THE MENTAL PART IS THE HARDEST TO COPE WITH.

  72. I have been taking methadone for about 10 years. As well as oxycodone. I am on disability and take it for my ruptured discs. 80 mg of methadone per day and 90 mg of oxycodone per day. I first began taking it for recreation. Now I really need it. However after I began my prescription form many years ago I continued to snort the drug. It works faster. Obviously there is no high at all. But my habit of insufflation has stuck with me.i REALLY need to know if there is any research about long term effects of insufflation of methadone and or oxycodone. Please. I hope you guys can help with some info. I can’t even talk to anyone else about this.. Thanks

  73. I have a question I have been on Methadone for about 4 months now and I’ve went from 15 mg to 60 mg and I’ve noticed that after I passed 35 mg I began having edema in my feet and swollen ankles reading the side effects I have not experienced the excessive sweating but my libido has dropped I am a healthy 30 yo male and now I feel like I have no interest in being intimate at all is this normal that Edema or swollen feel/ankles are side effects of Methadone maybe I need a decrease?

  74. thx but already knew this.and if stress levels increase the adrenaline destroys methadone causing very bad cramps

  75. Hey I have been on methadone for almost 3 months, I am not worried about what peolpe say about methadone, the reason is because when you hear about people dieing on methadone is most of the time they are takeing other drugs with the methadone, I feel if I dont take anything with it like xanax, which I was on xanax before I started taking methadone… but I am on 60mg and i am going up 5mg, I need to know dose methadone make you forget stuff? Or has it been reported that people started forgeting stuff when starting the methadone? Thank you very much, I look a lot of stuff up about methadone and I can not find anything about forgetting stuff….
    Thank you,
    Frances Calaway

  76. I must say Methadone literally saved my life, If I did not get on the clinic in my mid 20’s I would of wound up in 1 of 3 places. Eather Dead in Prison and the best possible outcome a homeless scum bag on the streets of the Bronx still living that miserable addict life style robbing and stealing for my next fix of dope. Every day I wake up and am living a productive lifestyle it’s because of the help methadone gave me to do so. I am 36 now and have been on the clinic for 11 years. I am now down to 18 MGS and hopefully will be off in 3 months with the slow detox cycle I am on. Those first 5 to 7 years I can not even express how important methadone was for helping me stay Sober. Saying all this it should only be used for a last resort when nothing else works.

  77. Loretta
    I think its because methadone is a prescription. And you have medicare and Medicaid so you get a Medicare scriot card that pays for your meds. I have the same, however, I think they HAVE to work
    with you. You recieve the medicaid because you are below the US recognized poverty level.
    I dont think the state of NY can differ greatly with Alabama when it comes to government aid. They take my medicare (also provided
    by the govt) and they CAN NOT bill me for whatever medicare wont
    cover. They usually dont foot the entire bill.

    Can you go to your local (county) gov’t center and ask for, or demand (nicely) some assistance with this?? They can help you.

    Let us know how it turns out.

  78. I live in Huntsville, Al. and i have on the clinic twice, i have been on it for 3 years now, and i go for pain. I finally got my s,s. disabilty so i have medicare and medicaid , before i didnt have insurance. now the clinic that i go to is accepting medicaid only and also give paitents a check for gas, what i dont understand is why they want accept medicaid if you have medicare. i would like to know if anyone could explain to me why this is bc i dont understand what so ever. thanks

  79. Hi Addiction

    I have benn begging, yes, literally begging my program, of 15 yrs to take me down!! 40 mgs in 6 months?? I’m still on a very high dose of 100. Have been compliant the whole time, except first year,until I was stable. Hate to say it but I really think its the money they get.

    I come once every 2 weeks, I get a urine once a month and a session w/ a counselor every few months!! It is a struggle for them to
    take me down. Even though I keep telling them my dose is too high. I even tell them I’m afraid of a car accident, I can not handle it.
    BTW I’m not the only “compliant” client with this complaint at this faciluty, Thanks……

  80. Hi Stephen. The prescribing doctor is responsible for setting up a dosage tapering schedule. No set dosage reduction schedule is established for everyone who takes methadone. Methadone, in particular, poses difficulties in dosing and increases the risk of toxicity when detoxing. But safe tapering from opiates generally follows a 2 to 3 week regimen with these principles:

    o Reduce the daily dose by 10%
    o Reduce the dose by 20% every 3-5 days
    o Reduce the dose by 25% per week
    o Avoid reducing the daily dose by > 50% at any given interval

  81. from michael sloan: methadone is unfornatly known to users as chemical handcuffs. I take 115 mils down from 140 for pain management i was hit by a car at 15 years old as a passenger on a motorcycle.I lost half of the leg and the other half was put on crooked ive taken all kinds of opiates for pain since i landed on my back my spine is finished full of arthritis,broke my nose which i had fixwed and it was painful. Many surgeries one to remove a bent steel plate and replace with a heavy duty plate.the blood i was given was full of hep c and so im just bidding my time waiting.

  82. i have been on methadone for 20 yrs now ranging from 120 to 14 mls a day ,yes i have had a couple of relapses but in the past few years i have been severly depressed and prone to the odd panic attack and now am starting to feel pain in my ankles( old injury, broke both ). this has all started since i began my de-tox off methadone, they say it does’nt get u high but keeps you stable is a load of bull. i did’nt realise how high i must have been as since i’ve got dwn to 30 mls from 90 my head is muddled my mind has never been so clear and i’m struggling mentally and physically to cope with it, is there anybody who feels or is having the same problems.

  83. The constipation is incredibly BAD. You have to find a creative way to fight it. I’ve been on Methadone for nine years, Good Luck.

  84. Hello Tina. Yes, methadone can cause adverse side effects which you describe. Methadone can impact the metabolic and nutritional system of the body, causing weight gain. Methadone can also impact the urogenital system and reduce libido. Depression can be a sign or symptoms associated with acute withdrawal from opiates, but is often present and in the background for many people dealing with former drug use.

    Is your boyfriend open to seeking solutions for these conditions? Although depression may be caused by medication, we all have a personal responsibility to take ownership of our health, and to try to do something to make our lives better. But if he’s not willing to try, you cannot force him to.

  85. I have a couple questions,my boyfriend has been on methadone for 15 years and recently has increased his dose to 210 mg a day for pain due to amputation,. Does methadone cause depression, weight gain and reproductive disfunction, went to get his testostorone levels checked and no results as of yet. He is depressed and does not want to do anything, he says it is because of the methadone

  86. the message is for Tony. Yes Methadone affects your teststosterone, it lowers it a lot. Mine had dropped to four i`m crrently taken replacement hormone treatment.

  87. Um…the reason is plenty clear. Patients gain weight b/c methadone makes you fat. They dance all around it at every clinic everywhere, but that’s why patients gain weight. Maybe it’s to keep you from choosing to be a junkie instead of fat. I’ve been tempted to

  88. Hi I was on methadone for 2 years.Taking 100mg daily I got a testostorone test done last week bcause I started the gym again and thhy say a normal test level is between 8 and 24 and mine is a Wopping 2….Which my Dr said is extremely LOW!…Does anyone else think it might be due to methadone.

  89. I go to a private for profit clinic run by CRC in Portland,Oregon. I go every 27 days. One group for an hour and a one on one for a half hour a month. With Kaiser I pay a co pay of $67 a month. Keep your nose clean and your body and methadone maintenance is no more trouble than getting a haircut or mowing the lawn. I don’t see the jaundiced eye or the “county”.

  90. In response to Craig- june 26-2011
    Perhapse methadone is an appropriate therapy for some people. To me it fealt like an unbearable prison. Shuffling into the clinic once a week, to be viewed with a suspicious and jaundiced eye. Made to “share” in those insipid group N.A. setions . I am an Athiest and being instructed by some slack jawed, mouth breathing, county drone that I must embrace my “higher power” and work steps is to me, oppressive and deeply repugnant. I to am a proffesional in my field and have worked hard to gain modest success. The very idea of one of those county trolls making descisions that effect my life and livelyhood makes me dispondent. Thankfully, I will never be condescended to or treated like “bad child” by some troglitic public “servant” FREE AT LAST

  91. My last blog was June 4TH. I have since gone to and returned from Jamaica where i recieved ibogaine therapy. Today is July 5 -My last methadone was on june 21. I am now completely drug free !! ibogaine is truly a miraculous substance! I am currently feeling a little weak and sleep is hard to come by By God, NO WITHDRAWL- NO DEPRESSION
    I have great mental accuity and have never fealt TRIUMPH like this.
    The treatment model in the U.S. for addiction is EFFEED UP! Avoid buprenex-it is a farce! Go to the Dr. you dont really get a health care provider as much as an agent for BIG PHARMA. Wise up truth seekers, get of the hamster wheel and seek release with ibogaine.

  92. I am 59yo white male. To look at me you would say I look in my mid 40’s and in good health. I quit smoking many years ago and haven’t had an alcoholic drink(a sip, one sip, of beer doesn’t count) since starting Methadone 31 years ago. I have been on a dose of 80mg. for that many years. I noticed my sexual desire waning about 10 years ago, although my wife and I still have some good “wrestling matches” once or twice a month. I have developed a couple friends who are chronic pain patients so if I want to use a little Oxy on Friday night I can. Yes, only on Friday night. I have a well paying job as a craftsman and an accident while “dirty” would put an end to my employment. I have had three accidents in 31 years and Methadone or any other drugs have never been an issue.
    Before Methadone I was involved in many drug store burglaries and a couple, I don’t even want to say, of drug stores. Within two weeks of starting Methadone I had a job, my one year old Son and Wife moved back in with me and I now have built equity in my life, house and possessions.
    In England they have Dipipanone. I’ve heard it is half the addiction liability of Methadone and a good stepping off drug for Methadone. I have accepted the fact that I will take Methadone until I die. Given the positive effects it has had on my life that is just fine with me.

  93. I have been on methadone steady for over 11 years. my current dose is 70mg daily. I have been as high as 130mg and as low as 20mg. Volume of daily intake has a very little to do with severity of side effects or severity of withdrawl (if abruptly discontinued). Like so many methadone brothers and sisters, I suffer from drenching sweats brought on by the least of physical exertion. I have gained about 80 pounds on methadone (never heavy before). Methadone has lowered my testosterone to a level of virtual sexual disfunction. Other side-effects of “Low-T” that I suffer from are; reduction of lean muscle, depression, lack of motivation, lack of constructive decisiveness. I recently had an EKG disclose “Left Bundle Branch Block” . A heart disfunction brought on from methadone. I am leaving for the Carribean shortly to recieve Ibogaine treatment. If you are not familiar with Ibogaine and wish to break your opiate addiction, I strongly recommend getting informed about this substance. Seek testimonials about the near miraculous power of this humble root-bark extractive. There is no shortage of good info on line but unfortunately, Ibogaine is not attainable (legally) in the U.S. currently. But it has been used with astonishing success in Europe, Canada, Mexico and scores of other fine nations. Until I discovered Ibogaine I was resolved to the dismal proposition of perpetual methadone addiction. And not having health insurance, methadone costs me $400.00 each month. If you are seeking a way out of the insanity of opiate addiction, dont lose hope – look into IBOGAINE

  94. i was on methadone about a year and a half ago,then i had a breast reduction and promised my husband i would get off methadone so i did then got on narcos 10/325 times2 4 times a day and also somas 350mgs 3 times a day,well now i have endometriosis and have had nothing but problems with my breast reduction(sucky plastic surgeon) but also have bad back problems,so i was paying for all these narcos and as costing me over $200 a month so my doctor decided i can take methadone 10mg 3 times a day plus the somas 350mg 3 times a day also,well my husbands ex wife she died while taking methadone,she had hep C,hep A,plus she drank alcohol ALOT she couldn’t go a day without it,well he is telling me that the methadone is going to kill my liver,and other people that have tried in the past to get me to use marijuana instead of methadone say that it makes your brain basically melt and i will start forgetting things,and it will kill me!!! This scares me alot but i have turned to every other avenue but don’t want to ruin my body either i am only 26 years old and please keep in mind i am not on methadone because i am getting off of drugs it is for pain management only,plus i wanted to know how often am i allowed to take methadone i am taking it every 6 hours right now and just making sure i am not overdosing myself,but for some reason the methadone keeps my pain away longer than the narcos, I also am concerned about gaining weight i have already gained about 55 pounds since i had my breast reduction so i do want to loose weight but i want to do it the right way!!!I am also concerned about 2 other things taking the somas with the methadone my doctor says its ok but just need another opinion,and 2nd thing is i am worried that methadone will effect my intimate relationship with my husband is there n e thing i can do to help me in this department?? I really apreciate you answering all these questions i know its alot but i am at a dead end here.
    Thank you,

  95. Hello I take 195 of methadone every morring by month at 6am for about 3 years now and have been stable on the 195 for 2 years. But for the past 2 years I have been bleeding from fibroids and I never stop. So I had to have a blood transfusion my hemoglobin was a 4.0 1/3 less then what I needed to have. I had this done on the 15th of April and for the first week I was feeling ok but the next week till now I have starting to feel withdraw at around 5pm everynigh. What I would like to know is because my body was so uesd to not have a high hemoglobin for the 2 years when I got all that blood back so fast and my liver,heart,kidneys, started to work better would that make me feel that withdraw. because now my body is working different and more of the methadone is being taken by my blood and by my liver. I dont know what other thing could make me feel like this I have not had withdraw for years and till right after my blood transfusion my methadone was holding me till the next day and sometimes even longer.

  96. Thanks for your question, Madi. I will forward it to Dr. Burson and see if she can answer it for you in another post.

  97. I’ve been on methadone for 3 years. I gained over 100 pounds within the first 6 months of being on it. I’m also a diabetic so my diet is very strict so I really can’t see blaming that for the weight gain. I also was diagnosed with hypothyroidism (under activity of the thyroid) right after I started taking the methadone. I was tested for it 6 months before I started it and my thyroid was within normal range. So I really think due to the timing and everything that happend, that the methadone killed my thyroid. The clinic I go to refuses to even hear me out, They say methadone has no side effects and that I must be sneaking sweets and just not realizing it. I’m really frustrated with the whole situation. If anyone has any advice or is in a simalar situation please comment here.

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