Addiction = Physical and psychological dependence are seen in people using higher amounts of hydrocodone for a longer period of time.
Mechanism of Hydrocodone action
Hydrocodone interacts as an opiate agonist at specific receptor binding sites in the central nervous system. Specifically, it interacts with the delta-receptors, localized in the limbic regions; the mu-receptors, from the pain modulating regions; the kappa-receptors, localized in the deep layers of the cerebral cortex; and the sigma-receptors, which is thought to mediate the dysphoric and psychotomimetic effects of some opiate partial agonists.
How addictive is Hydrocodone?
MODERATE/HIGH – Hydrocodone is highly addictive. Hydrocodone can be habit-forming, causing physical and psychological dependence. Its abuse liability is similar to morphine and less than oxycodone.
Is damage caused by Hydrocodone permanent or reversible?
Permanent
- acute liver failure
- damage caused by cardiac arrest
- damage caused by respiratory failure
Possible
- bleeding gums
- compromised mental function
- depression
- headaches
- lowered immunity
- pale or blue lips
- severe allergic reactions
Reversible
- constipation and loss of appetite
- dry mouth
- constipation
- nausea and vomiting
- irregular heart rate
- blood clotting issues
How Hydrocodone addiction affects you?
Health
- coma or death from overdose on hydrocodone
- inability to fight viral and bacterial invaders
- visceral organ damage or failure
- weight loss
Work
- impaired mental abilities
- inattentiveness
- problems at work
- weakened physical performance
Self esteem
- dissatisfaction with life
- low self-esteem
- negative body image
- social withdrawal
Relationships
- brokenness within the family unit
- damaged relationships
- isolation from family and friends
- personality shifts
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