How Spice acts in the brain?
Synthetic cannabinoids target the same cannabinoid receptors in the brain as THC from natural marijuana. Although more scientific research is needed and Spice is a relatively new drug, we already know that synthetic cannabinoids bind more strongly to brain cell receptors in comparison to THC. Because Spice acts more strongly in the brain, it can also produce more potent (and potentially hazardous) effects.
Mental health effects of Spice
Spice users frequently report experiencing mental health problems, regardless if they are using it for a longer period of time or only tried it one time. Testimonials commonly report the occurrence of symptoms, such as:

- altered perception
- confusion
- delusional thinking
- detachment from reality
- extreme distrust in people
- hallucinations
- intense fear
- paranoia
- suicidal and homicidal thoughts and actions
In several cases, there have also been reports of long term damage to mental health, with continuing hallucinations appearing after several months of trying Spice.
Long term Spice effects and questions
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