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Long term effects of hydrocodone on the brain (INFOGRAPHIC)

Long term effects of hydrocodone on the brain (INFOGRAPHIC)

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Specific long term effects of hydrocodone on the brain

Hydrocodone’s effects on the nervous system

  • can cause respiratory depression
  • can cause unconsciousness
  • delirium
  • difficulty thinking
  • impaired mental abilities
  • slows brain activity

Hydrocodone’s effects on the neurotransmitters

  • acts on mu-receptors
  • acts on sigma-receptors
  • acts on kappa-receptors
  • acts on the delta-receptors

Hydrocodone’s effects on the personality

  • changes in personality
  • low self-confidence
  • social isolation

Hydrocodone’s effects on behavior

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  • abnormally cheerful mood
  • abnormally despondent mood
  • anger
  • anxiety
  • emotional liability
  • paranoid behavior
  • unusual thoughts

Psychological effects

  • addiction
  • cravings and compulsion
  • decrease in awareness or responsiveness
  • mental depression
  • sudden mood swings
  • vivid dreams

 

What are typical doses?

Abuse typical doses

  • per day first time users …… 5-10 mg
  • per day tolerant users ……… 10-15 mg
  • per day addicts …… 20-30 mg

Lethal typical doses

  • reported fatal dose ………… 90 mg
  • 9 times the maximum dose prescribed

 

How long is “long term”?

Generally, long term use of hydrocodone is daily dosing which continues for more than 6 months. But long term opioid use is measured differently in various combinations with other chemical substances.

Chronic = repetitive and pattern-followed hydrocodone abuse that reflects negative consequences on:

  • financial balance
  • health condition
  • social connections

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